In the field of tumor immunotherapy, adoptive cell transfer (ACT) therapy, especially T cell-based cell therapy strategies, has shown sustained clinical efficacy. Two genetically modified T cells (CAR-T cells and TCR engineered T cells) have been developed for adoptive transfer, and substantial progress has been made in the treatment of malignant tumors. Therefore, the in-depth exploration of the structure and function of these TCRs plays an important role in the further development of T cell therapy strategies, especially CAR-T therapy. Learn more about CD3ε -based CAR-T: https://www.creative-biolabs.c....om/car-t/cd3e-based-
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