Alprostadil injections are sometimes used in combination with penile implants. However, using Alprostadil with a penile implant can increase the risk of priapism (prolonged erection), which can be painful and may lead to tissue damage.Alprostadil can affect blood pressure and heart rate. People with cardiac devices like pacemakers or implantable cardioverter defibrillators (ICDs) should be cautious due to potential changes in heart rate or rhythm.
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